An Investigation of Dispensational Premillennialism: an Analysis and Evaluation of the Eschatology of John F. Walvoord

This study presents a historical and theological inquiry of one of the most influential eschatological views in America\u27s evangelical and premillennial fundamentalist circles: dispensational premillennialism. My objective is threefold: (1) to survey the main factors that contributed to the rise of dispensational premillennialism, (2) to evaluate its claims to the historical and theological roots, and (3) to portray and to assess the eschatology ofthis system as it has been enunciated by John F. Walvoord. To achieve these purposes, after a brief introductory chapter, we begin in chapter 2 by showing the development of premillennialismsince the days of the early church until thenineteenth century. Chapter 3 examines the role and impact offuturism upon premillennialism. The chapter also discusses the claims of Dispensationalism concerning its continuity with the premillennialism of the early church. The historical rise of dispensational premillennialism is traced to John Nelson Darby. The last part of the chapter surveys the theological roots of this system. It shows that some features of the chiliasm of theearly church that seem to come from Jewish apocalypticism appear in dispensational premillennialism. Special attention is given to Lacunza\u27s millenarian ideas that show a close parallel with most of the tenets of modern Dispensationalism. Chapter 4 describes the premillennial eschatology of John F. Walvoord who is a widely known contemporary representative of classic Dispensationalism. Chapter 5 utilizes the findings of chapters 3 and 4 and provides a critical evaluation of the historical and theological backgrounds of dispensational premillennialism within the history of Christian doctrinal development from the Scriptures. Walvoord\u27s hermeneutics, ecclesiology, pretribulational eschatology, and the nature of the millennial kingdom are evaluated on their own merits. The final chapter presents the summary and conclusions of this study

A Novel Two-Component System Involved in the Transition to Secondary Metabolism in Streptomyces coelicolor

BACKGROUND: Bacterial two-component signal transduction regulatory systems are the major set of signalling proteins frequently mediating responses to changes in the environment. They typically consist of a sensor, a membrane-associated histidine kinase and a cytoplasmic response regulator. The membrane-associated sensor detects the environmental signal or stress, whereas the cytoplasmic regulatory protein controls the cellular response usually by gene transcription modulation. METHODOLOGY/PRINCIPALFINDINGS: The Streptomyces coelicolor two genes operon SCO5784-SCO5785 encodes a two-component system, where SCO5784 encodes a histidine-kinase sensor and SCO5785 encodes a response regulator protein. When the expression level of the regulator gene decreases, the antibiotic synthesis and sporulation is delayed temporarily in addition to some ribosomal genes became up regulated, whereas the propagation of the regulatory gene in high copy number results in the earlier synthesis of antibiotics and sporulation, as well as the down regulation of some ribosomal genes and, moreover, in the overproduction of several extracellular proteins. Therefore, this two-component system in S. coelicolor seems to influence various processes characterised by the transition from primary to secondary metabolism, as determined by proteomic and transcriptomic analyses. CONCLUSIONS/SIGNIFICANCE: Propagation of SCO5785 in multicopy enhances the production of antibiotics as well as secretory proteins. In particular, the increase in the expression level of secretory protein encoding genes, either as an artefactual or real effect of the regulator, could be of potential usefulness when using Streptomyces strains as hosts for homologous or heterologous extracellular protein production

Secuestro de C en plantaciones de Eucalyptus spp establecidas en terrenos agrícolas en el norte de España

Una de las estrategias que se ha planteado para fijar gases con efecto invernadero (CO2, CH4 y N2O) es el aumento de la superficie forestal. España es uno de los países que más han contribuido a incrementar la superficie forestal en Europa, lo que se debe en buena parte al establecimiento de parcelas en tierras agrarias en situación de marginalidad. Durante el período de 11 años, transcurridos entre el segundo y el tercer inventarios forestales (1987 y 1998), el almacenamiento de C en biomasa arbórea en el norte de España ha aumentado en un 50 %. En este trabajo se realiza una primera estimación de las ganancias de C en biomasa y suelo en plantaciones de eucalipto establecidas en terrenos agrícolas. Para ello se seleccionaron un total de 25 pares de parcelas. Se trata de parcelas agrarias en las cuales parte de la superficie se transformó a plantación de Eucalyptus sp. En estas parcelas se determinó la acumulación de C en biomasa arbórea, mantillo y suelo en tres profundidades 0-5, 5-15 y 15-30 cm. Dado las mejores condiciones de fertilidad y mayor profundidad, que promueven el crecimiento arbóreo, la tasa de acumulación de C en biomasa es considerablemente superior a las plantaciones establecidas en suelos forestales. Los datos de este trabajo muestran acumulaciones superiores a 17 Mg ha-1 año-1. La acumulación de C en el mantillo también es superior a 1 Mg ha-1 año-1. En cuanto al suelo mineral, las pérdidas de C se reducen con los años desde el cambio de uso, fundamentalmente a partir de los 15 años del establecimiento y en plantaciones sobre esquistos y pizarras. Hasta ese momento se produjeron ligeras pérdidas.____________________________________One of the strategies proposed for fixing gases that contribute to the greenhouse effect (CO2, CH4 and N2O) is to increase the extension of land covered by forest. Spain is one of the countries that has contributed most to the increase in the forest area in Europe, largely due to the establishment of forest plots on marginal agricultural land. During the 11- year period between the second and third forest inventories (1987 and 1998), there has been a 50% increase in the storage of C in tree biomass in northern Spain. In the present study, a first estimate was made of the increase in C in biomass and soil in eucalyptus plantations established on agricultural land. A total of 25 pairs of plots were selected for the study. The plots are on agricultural land, part of which has been transformed by plantation of Eucalyptus sp. The amount of C accumulated in the tree biomass, humus and three different depths of soil (0-5, 5-15 and 15-30 cm) was determined. Given the more fertile conditions and the greater depth of the soil, which favour tree growth, the rate of accumulation of C in the biomass was considerably higher than in plantations established on forest soils. The data obtained in the present study revealed accumulations of C of more than 17 Mg ha-1 year-1. Accumulation of C in the humus was also higher than 1 Mg ha-1 year-1. The losses of C in the mineral soil decreased since the change in land use, generally from 15 years after establishment onwards, and in plantations on schists and slates. Slight losses of C were observed up until this time

Edible Mushrooms as Functional Ingredients for Development of Healthier and More Sustainable Muscle Foods: A Flexitarian Approach

Not Availableonsumers are increasingly interested in nutritious, safe and healthy muscle food products with reduced salt and fat that benefit their well-being. Hence, food processors are constantly in search of natural bioactive ingredients that offer health benefits beyond their nutritive values without affecting the quality of the products. Mushrooms are considered as next-generation healthy food components. Owing to their low content of fat, high-quality proteins, dietary fibre and the presence of nutraceuticals, they are ideally preferred in formulation of low-caloric functional foods. There is a growing trend to fortify muscle food with edible mushrooms to harness their goodness in terms of nutritive, bioactive and therapeutic values. The incorporation of mushrooms in muscle foods assumes significance, as it is favourably accepted by consumers because of its fibrous structure that mimics the texture with meat analogues offering unique taste and umami flavour. This review outlines the current knowledge in the literature about the nutritional richness, functional bioactive compounds and medicinal values of mushrooms offering various health benefits. Furthermore, the effects of functional ingredients of mushrooms in improving the quality and sensory attributes of nutritionally superior and next-generation healthier muscle food products are also highlighted in this paper.Not Availabl

Exploiting the potential of bioactive molecules extracted by ultrasounds from avocado peelsfood and nutraceutical applications

Natural bioactive compounds from food waste have fomented interest in food and pharmaceutical industries for the past decade. In this work, it purposed the recovery of bioactive avocado peel extract using an environmentally friendly technique: the ultrasound assisted extraction. The response surface methodology was applied in order to optimize the conditions of the extraction, ethanol-water mixtures and time. The optimized extracts (ethanol 38.46%, 44.06 min, and 50 °C) were chemically characterized by HPLC-ESI-MS and FTIR. Its antioxidant ability, as well as, its effect on cell metabolic activity of normal (L929) and cancer (Caco-2, A549 and HeLa) cell lines were assessed. Aqueous ethanol extracts presented a high content in bioactive compounds with high antioxidant potential. The most representative class of the phenolic compounds found in the avocado peel extract were phenolic acids, such as hydroxybenzoic and hydroxycinnamic acids. Another important chemical group detected were the flavonoids, such as flavanols, flavanonols, flavones, flavanones and chalcone, phenylethanoids and lignans. In terms of its influence on the metabolic activity of normal and cancer cell lines, the extract does not significantly affect normal cells. On the other hand, it can negatively affect cancer cells, particularly HeLa cells. These results clearly demonstrated that ultrasound is a sustainable extraction technique, resulting in extracts with low toxicity in normal cells and with potential application in food, pharmaceutical or nutraceutical sectors.The authors acknowledge the financial support received from “Xunta de Galicia” (GRC ED431C 2017/62-GRC, and Project ED431F 2020/03). These projects are partially funded by the FEDER Program of the European Union (“Unha maneira de facer Europa”). This research was also funded by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UIDB/04469/2020 unit. Beatriz Gullón would like to express her gratitude to the Spanish Ministry of Economy and Competitiveness for her postdoctoral grant (Reference RYC2018-026177-I).info:eu-repo/semantics/publishedVersio

Propuesta de intervención educativa para trabajar la comprensión lectora en un niño con dislexia de 6º de Educación Primaria a través del estudio de un caso

Leer es una habilidad que se adquiere con mucho trabajo, ya que implica la interacción de varios procesos cognitivos que van a permitir, posteriormente, la comprensión del texto. No obstante, hay personas que tienen dificultades a la hora de adquirir y consolidar el lenguaje escrito o la lectura. Uno de los trastornos del aprendizaje más estudiados y con mayor prevalencia que afecta a la adquisición de la lectoescritura es la dislexia. Así pues, el presente trabajo tiene el objetivo de investigar y describir cómo afecta la dislexia al proceso lector y, más concretamente, a la comprensión lectora. Asimismo, se presenta el planteamiento de una intervención educativa dirigida a un alumno concreto diagnosticado con dislexia, con la que se busca mejorar el procesamiento sucesivo y, así, fomentar el resto de los procesos cognitivos implicados en la lectura para mejorar su comprensión.Reading is a skill that is acquired with hard work, since it involves the integration of several cognitive processes that will allow the reading and comprehension of a text. However, there are people who have difficulties in acquiring and consolidating written language or reading. One of the most studied and most prevalent learning disorders affecting the acquisition of reading and writing is dyslexia. The aim of this paper is to investigate and describe how dyslexia affects the reading process and, more specifically, reading comprehension. It also presents the approach of an educational intervention aimed at a specific student diagnosed with dyslexia to improve his successive processing, in order to promote the rest of the cognitive processes involved in reading and improve his reading comprehension